risks of nitrate poisoning

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	risks of nitrate poisoning

jessclipz

7-16-2009 12:41 AM

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Physiologically, <I>nitrates</I> are reduced to <I>nitrites</I> in the stomach.  Nitrite enters the bloodstream and binds to hemoglobin, changing it to methemoglobin. The effect is interference with the blood's ability to carry oxygen to the body tissues. 
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Studies suggest a potential link between high nitrates in drinking water and an increased incidence of gastrointestinal cancer.  The theory is that the nitrite byproduct combines with amines in the body to form N-nitroso compounds - known for certain to be cancer-causing agents.  Despite the data concerning abnormal levels of gastric cancer in regions with high nitrates in the drinking water, the connection is not yet deemed conclusive.  However, researchers feel it is prudent to view nitrate-nitrogen levels greater than 10 mg/l as a possible cancer risk factor.
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