Can Depression Change Your DNA?


	Can Depression Change Your DNA?

dmegivern

8-6-2008 8:42 PM

6921 views

tags:

mental illness, genetics, epigenetics, depression

2 Comments |

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8-10-2008 8:57 AM

tabsey

Thanks for that. It is what I had half guessed, but the better explanation helps understanding.

8-10-2008 5:01 PM

LillianL

Your article is right on track with my crazy notion that everything is connected. Thanks!

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<div style="margin: 12px 0px; font-family: arial; color: #333333; background: #ffffff; border: solid 4px #e5e5e5; width: 100%; clear: left;"><div class="CM_CTB_Content_Wrap" style="margin: 0px; padding: 0px;background-color: #ffffff;"><div style="border-bottom: solid 1px #dcdcdc; white-space: nowrap; margin-bottom: 8px; background-color: #eeeeee ;background-image: url(http://www.clipmarks.com/images/source-bg.gif); background-repeat: repeat-x; height: 24px; line-height: 24px; vertical-align: middle; padding-bottom: 4px; color: #666666; font-size: 10px;" ><a href="http://clipmarks.com/clip-to-blog/" title="see clips that are hot right now"><img src="http://content.clipmarks.com/blog_embed/bf67fb59-0347-42d4-b64e-a778301d3ce0/02F9B2BF-7626-43DE-8727-05449D6C1B77/" alt="" width="19" height="19" border="0" style="vertical-align: middle; margin: 0px 4px; display: inline; border: none; float:none;" /></a>clipped from <a title="http://psychcentral.com/news/2008/07/31/can-depression-change-your-dna/2678.html" href="http://psychcentral.com/news/2008/07/31/can-depression-change-your-dna/2678.html" style="font-size: 11px;">psychcentral.com</a></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://psychcentral.com/news/2008/07/31/can-depression-change-your-dna/2678.html"><H1 id="post-2678"><A title="Permanent Link: Can Depression Change Your DNA?" rel="bookmark" href="http://psychcentral.com/news/2008/07/31/can-depression-change-your-dna/2678.html">Can Depression Change Your DNA?</A></H1></blockquote><div style="border-bottom: solid 1px #dcdcdc; white-space: nowrap; margin-bottom: 8px; background-color: #eeeeee ;background-image: url(http://www.clipmarks.com/images/source-bg.gif); background-repeat: repeat-x; height: 24px; line-height: 24px; vertical-align: middle; padding-bottom: 4px; color: #666666; font-size: 10px;" ><a href="http://clipmarks.com/clip-to-blog/" title="see clips that are hot right now"><img src="http://content9.clipmarks.com/images/clip-icon.gif" alt="" width="19" height="19" border="0" style="vertical-align: middle; margin: 0px 4px; display: inline; border: none; float:none;" /></a>clipped from <a title="http://psychcentral.com/news/2008/07/31/can-depression-change-your-dna/2678.html" href="http://psychcentral.com/news/2008/07/31/can-depression-change-your-dna/2678.html" style="font-size: 11px;">psychcentral.com</a></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://psychcentral.com/news/2008/07/31/can-depression-change-your-dna/2678.html"><div align="center"><img src="http://content6.clipmarks.com/blog_cache/psychcentral.com/img/1901B5A6-B159-4F28-88CC-120050514144" alt="Brain" /></div></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://psychcentral.com/news/2008/07/31/can-depression-change-your-dna/2678.html">
 <IMG alt="Brain" src="http://psychcentral.com/news/u/2007/07/naturalbrainchemicalmanagedispair.jpg" id="newsimg" />New research points to significant modifications of an important gene that suggests depression may play a role in changing the very makeup of the brain. </blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://psychcentral.com/news/2008/07/31/can-depression-change-your-dna/2678.html"><P>Researchers at the Robarts Research Institute at The University of Western Ontario compared the brains of people who committed suicide with those who died suddenly of natural causes, such as a heart attack. They found that the genome in suicidal, depressed people was chemically modified by a process that is normally involved in regulating the essential characteristics of all cells in the body.</P></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://psychcentral.com/news/2008/07/31/can-depression-change-your-dna/2678.html"><P>This is apparently the first study to show that proteins that modify DNA directly are more highly expressed in the brains of people who commit suicide. These proteins are involved in chemically modifying DNA in a process called epigenomic regulation. </P></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://psychcentral.com/news/2008/07/31/can-depression-change-your-dna/2678.html">The rate of methylation in the suicide brains was found to be much greater than that of the control group.</blockquote></div><div style="margin: 0px 6px 6px 4px;"><table style="font-size: 11px;border-spacing: 0px;padding: 0px;" cellpadding="0" cellspacing="0" width="100%"><tr><td style="background:transparent;border-width:0px;padding:0px;">&nbsp;</td><td align="right" style="background:transparent;border-width:0px;padding:0px;width:107px" width="107"><a href="http://clipmarks.com/share/02F9B2BF-7626-43DE-8727-05449D6C1B77/blog/" title="blog or email this clip"><img src="http://content7.clipmarks.com/images/c2b-foot.png" border="0" alt="blog it" width="107" height="17" style="border-width:0px;padding:0px;margin:0px;" /></a></td></tr></table></div></div>

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