Scientists Cure mice with Sickle Cell anemia


	Scientists Cure mice with Sickle Cell anemia

pokkets

12-9-2007 6:13 PM

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sickle, stem, cell, reprogram, mice, cure

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<div style="margin: 12px 0px; font-family: arial; color: #333333; background: #ffffff; border: solid 4px #e5e5e5; width: 100%; clear: left;"><div class="CM_CTB_Content_Wrap" style="margin: 0px; padding: 0px;background-color: #ffffff;"><div style="border-bottom: solid 1px #dcdcdc; white-space: nowrap; margin-bottom: 8px; background-color: #eeeeee ;background-image: url(http://www.clipmarks.com/images/source-bg.gif); background-repeat: repeat-x; height: 24px; line-height: 24px; vertical-align: middle; padding-bottom: 4px; color: #666666; font-size: 10px;" ><a href="http://clipmarks.com/clip-to-blog/" title="see clips that are hot right now"><img src="http://content.clipmarks.com/blog_embed/5374be56-0a08-4a86-a0d4-ade946095177/0998F0BE-6358-44B8-98A0-FF52876BC8A8/" alt="" width="19" height="19" border="0" style="vertical-align: middle; margin: 0px 4px; display: inline; border: none; float:none;" /></a>clipped from <a title="http://www.mail.com/Article.aspx?articlepath=APNews\Health\20071207\Stem_Cells_Sickle_Cell_20071207.xml&cat=health&subcat=&pageid=1" href="http://www.mail.com/Article.aspx?articlepath=APNews\Health\20071207\Stem_Cells_Sickle_Cell_20071207.xml&cat=health&subcat=&pageid=1" style="font-size: 11px;">www.mail.com</a></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.mail.com/Article.aspx?articlepath=APNews\Health\20071207\Stem_Cells_Sickle_Cell_20071207.xml&cat=health&subcat=&pageid=1"><DIV class="author">By LAURAN NEERGAARD    </DIV><P>Scientists have the first evidence that those "reprogrammed stem cells" that made headlines last month really have the potential to treat disease: They used skin from the tails of sick mice to cure the rodents of sickle cell anemia.</P><P>At issue: Turning adult cells into ones that mimic embryonic stem cells, master cells that can turn into any type of tissue. When scientists announced last month that they had successfully engineered embryo-like stem cells from human skin, it was hailed as a possible alternative to ethically fraught embryo research.</P><P>But no one yet knew whether those reprogrammed cells could create functioning tissue</P></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.mail.com/Article.aspx?articlepath=APNews\Health\20071207\Stem_Cells_Sickle_Cell_20071207.xml&cat=health&subcat=&pageid=1">just like natural embryonic stem cells can</blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.mail.com/Article.aspx?articlepath=APNews\Health\20071207\Stem_Cells_Sickle_Cell_20071207.xml&cat=health&subcat=&pageid=1"><P>The study, published in the journal Science, doesn't bring this potential therapy closer to people just yet. Big hurdles remain, including a risk of cancer from the reprogramming method.</P></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.mail.com/Article.aspx?articlepath=APNews\Health\20071207\Stem_Cells_Sickle_Cell_20071207.xml&cat=health&subcat=&pageid=1">But without the mouse work, scientists didn't know "whether all the recombined machinery will work or not,</blockquote></div><div style="margin: 0px 6px 6px 4px;"><table style="font-size: 11px;border-spacing: 0px;padding: 0px;" cellpadding="0" cellspacing="0" width="100%"><tr><td style="background:transparent;border-width:0px;padding:0px;">&nbsp;</td><td align="right" style="background:transparent;border-width:0px;padding:0px;width:107px" width="107"><a href="http://clipmarks.com/share/0998F0BE-6358-44B8-98A0-FF52876BC8A8/blog/" title="blog or email this clip"><img src="http://content8.clipmarks.com/images/c2b-foot.png" border="0" alt="blog it" width="107" height="17" style="border-width:0px;padding:0px;margin:0px;" /></a></td></tr></table></div></div>