The monkeys with three parents that could stop mothers passing on incurable diseases


	The monkeys with three parents that could stop mothers passing on incurable diseases

ofcapri

8-27-2009 8:20 AM

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tags:

dna

ofcapri says:

The team of scientists from the Oregon National Primate Research Centre in effect swapped the mitochondrial DNA (mDNA) from the macaque monkey mother's egg for the mDNA of a donor egg. Reconstructed eggs were then fertilised with the father's sperm and the healthy offspring were born. Tests showed that no mDNA from the mother's egg had been transferred.

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<div style="margin: 12px 0px; font-family: arial; color: #333333; background: #ffffff; border: solid 4px #e5e5e5; width: 100%; clear: left;"><div class="CM_CTB_Content_Wrap" style="margin: 0px; padding: 0px;background-color: #ffffff;"><div style="border-bottom: solid 1px #dcdcdc; white-space: nowrap; margin-bottom: 8px; background-color: #eeeeee ;background-image: url(http://www.clipmarks.com/images/source-bg.gif); background-repeat: repeat-x; height: 24px; line-height: 24px; vertical-align: middle; padding-bottom: 4px; color: #666666; font-size: 10px;" ><a href="http://clipmarks.com/clip-to-blog/" title="see clips that are hot right now"><img src="http://content.clipmarks.com/blog_embed/a10cdac6-3127-4efd-84f0-0bf9fc6d2f7f/0D776BF4-375D-4AB3-B8CE-3EE213B29988/" alt="" width="19" height="19" border="0" style="vertical-align: middle; margin: 0px 4px; display: inline; border: none; float:none;" /></a>clipped from <a title="http://www.guardian.co.uk/science/2009/aug/26/monkeys-genetics-dna-mitochondria-disease" href="http://www.guardian.co.uk/science/2009/aug/26/monkeys-genetics-dna-mitochondria-disease" style="font-size: 11px;">www.guardian.co.uk</a></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.guardian.co.uk/science/2009/aug/26/monkeys-genetics-dna-mitochondria-disease"><H1>The monkeys with three parents that could stop mothers passing on incurable diseases</H1></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.guardian.co.uk/science/2009/aug/26/monkeys-genetics-dna-mitochondria-disease"><UL class="article-attributes multi-pub">
	        		<LI class="byline">
			 								                	        	        	            <A name="&lid={contentTypeByline}{Karen McVeigh}&lpos={contentTypeByline}{1}" href="http://www.guardian.co.uk/profile/karenmcveigh">Karen McVeigh</A>
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<LI class="publication">        
			<A name="&lid={contentTypeByline}{guardian.co.uk}&lpos={contentTypeByline}{2}" href="http://www.guardian.co.uk">guardian.co.uk</A>,			
				            Wednesday 26 August 2009 22.14 BST	        	        
        </LI> 
<LI class="history"><A href="#history-byline" id="historylink-byline" class="rollover historylink">Article history</A></LI></UL></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.guardian.co.uk/science/2009/aug/26/monkeys-genetics-dna-mitochondria-disease"><div align="center"><img src="http://content8.clipmarks.com/blog_cache/www.guardian.co.uk/img/44F964E3-4831-4197-B717-D728C623FED1" alt="Macaque monkey twins Mito and Tracker" /></div></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.guardian.co.uk/science/2009/aug/26/monkeys-genetics-dna-mitochondria-disease"><P class="caption">Macaque twins Mito, left, and Tracker whose birth could lead to eradication of human genetic diseases. Photograph: William F. Sutton/Oregon Health &amp; Science University/AP</P></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.guardian.co.uk/science/2009/aug/26/monkeys-genetics-dna-mitochondria-disease"><P>Four baby monkeys created in a laboratory in the <A href="http://www.guardian.co.uk/world/usa">United States</A> could hold the key to the eradication of a class of incurable genetic diseases, scientists revealed today.</P></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.guardian.co.uk/science/2009/aug/26/monkeys-genetics-dna-mitochondria-disease"><P>In an experiment that brings the creation of babies with three biological parents a step closer, Spindler, Spindly and twins Mito and Tracker were born through IVF using a technique that should make it possible to prevent women who carry genetic disorders of the mitochondria from passing them on to their children.</P></blockquote></div><div style="margin: 0px 6px 6px 4px;"><table style="font-size: 11px;border-spacing: 0px;padding: 0px;" cellpadding="0" cellspacing="0" width="100%"><tr><td style="background:transparent;border-width:0px;padding:0px;">&nbsp;</td><td align="right" style="background:transparent;border-width:0px;padding:0px;width:107px" width="107"><a href="http://clipmarks.com/share/0D776BF4-375D-4AB3-B8CE-3EE213B29988/blog/" title="blog or email this clip"><img src="http://content9.clipmarks.com/images/c2b-foot.png" border="0" alt="blog it" width="107" height="17" style="border-width:0px;padding:0px;margin:0px;" /></a></td></tr></table></div></div>

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