The applications of cheap sequencing are almost limitless, from disease diagnostics to research that


	The applications of cheap sequencing are almost limitless, from disease diagnostics to research that

Silkweaver

7-15-2008 8:25 PM

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tags:

dna, sequencing

Silkweaver says:

The applications of cheap sequencing are almost limitless, from disease diagnostics to research that could yield microbes engineered to produce biofuels or medicines.

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<div style="margin: 12px 0px; font-family: arial; color: #333333; background: #ffffff; border: solid 4px #e5e5e5; width: 100%; clear: left;"><div class="CM_CTB_Content_Wrap" style="margin: 0px; padding: 0px;background-color: #ffffff;"><div style="border-bottom: solid 1px #dcdcdc; white-space: nowrap; margin-bottom: 8px; background-color: #eeeeee ;background-image: url(http://www.clipmarks.com/images/source-bg.gif); background-repeat: repeat-x; height: 24px; line-height: 24px; vertical-align: middle; padding-bottom: 4px; color: #666666; font-size: 10px;" ><a href="http://clipmarks.com/clip-to-blog/" title="see clips that are hot right now"><img src="http://content.clipmarks.com/blog_embed/4c32308e-73e8-467a-931d-a6833fc7a7f3/18DDC636-A05B-46CB-B5F3-86262B0C3D3E/" alt="" width="19" height="19" border="0" style="vertical-align: middle; margin: 0px 4px; display: inline; border: none; float:none;" /></a>clipped from <a title="http://www.technologyreview.com/Biotech/20947/?a=f" href="http://www.technologyreview.com/Biotech/20947/?a=f" style="font-size: 11px;">www.technologyreview.com</a></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.technologyreview.com/Biotech/20947/?a=f"><div align="center"><img src="http://content8.clipmarks.com/blog_cache/www.technologyreview.com/img/ED4409E3-A490-46A9-A7C2-DC9FC2ADA7F3" alt="" /></div></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.technologyreview.com/Biotech/20947/?a=f">In the corner of Helicos BioSciences' offices in Cambridge, MA, a screen on the face of what looks like a giant refrigerator flashes a countdown: 10 days, five hours, and 51 minutes until it finishes reading the sequence of all the DNA that has been fed into it.</blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.technologyreview.com/Biotech/20947/?a=f">The high-throughput machine, a complex configuration of tubes, lasers, and chemicals, contains two plates, each with 25 microfluidic channels etched into it.</blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.technologyreview.com/Biotech/20947/?a=f">Each channel is capable of holding and sequencing a separate DNA sample. Sequencing the samples in parallel, the machine takes just one hour to read 1.3 billion of the chemical "bases"--known as A, C, T, and G--that make up a strand of DNA.</blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.technologyreview.com/Biotech/20947/?a=f">Helicos has "basically built the world's fastest DNA sequencer.</blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.technologyreview.com/Biotech/20947/?a=f">The price of sequencing a human genome has dropped in recent years, from the $300 million the Human Genome Project spent on its first draft to less than $100,000.</blockquote></div><div style="margin: 0px 6px 6px 4px;"><table style="font-size: 11px;border-spacing: 0px;padding: 0px;" cellpadding="0" cellspacing="0" width="100%"><tr><td style="background:transparent;border-width:0px;padding:0px;">&nbsp;</td><td align="right" style="background:transparent;border-width:0px;padding:0px;width:107px" width="107"><a href="http://clipmarks.com/share/18DDC636-A05B-46CB-B5F3-86262B0C3D3E/blog/" title="blog or email this clip"><img src="http://content9.clipmarks.com/images/c2b-foot.png" border="0" alt="blog it" width="107" height="17" style="border-width:0px;padding:0px;margin:0px;" /></a></td></tr></table></div></div>

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