why menthol feels fresh


	why menthol feels fresh

wildcat

5-31-2007 9:48 AM

926 views

tags:

science, health, cold, nervous system, pain, medicine, sensory receptors, temperature

1 Comment |

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5-31-2007 2:26 PM

BitDrifter

Very interesting.

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<div style="margin: 12px 0px; font-family: arial; color: #333333; background: #ffffff; border: solid 4px #e5e5e5; width: 100%; clear: left;"><div class="CM_CTB_Content_Wrap" style="margin: 0px; padding: 0px;background-color: #ffffff;"><div style="border-bottom: solid 1px #dcdcdc; white-space: nowrap; margin-bottom: 8px; background-color: #eeeeee ;background-image: url(http://www.clipmarks.com/images/source-bg.gif); background-repeat: repeat-x; height: 24px; line-height: 24px; vertical-align: middle; padding-bottom: 4px; color: #666666; font-size: 10px;" ><a href="http://clipmarks.com/clip-to-blog/" title="see clips that are hot right now"><img src="http://content.clipmarks.com/blog_embed/d080af88-be76-4e87-aa74-71190c8a4be1/1AFCBB65-03F1-4E9A-A7F5-19EA644D4DC0/" alt="" width="19" height="19" border="0" style="vertical-align: middle; margin: 0px 4px; display: inline; border: none; float:none;" /></a>clipped from <a title="http://physorg.com/news99758315.html" href="http://physorg.com/news99758315.html" style="font-size: 11px;">physorg.com</a></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://physorg.com/news99758315.html"><H1>Detecting cold, feeling pain: Study reveals why menthol feels fresh</H1> 
<SPAN id="top_ad_unit"></SPAN>  <DIV id="Preview"> 
Scientists have identified the receptor in cells of the peripheral nervous system that is most responsible for the body's ability to sense cold.</DIV></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://physorg.com/news99758315.html"> 
The finding, reported on-line in the journal "Nature" (May 30, 2007), reveals one of the key mechanisms by which the body detects temperature sensation. But in so doing it also illuminates a mechanism that mediates how the body experiences intense stimuli – temperature, in this case – that can cause pain.</blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://physorg.com/news99758315.html">		
							As such, the receptor – known as menthol receptor TRPM8 -- provides a target for studying acute and <A class="iAs" classname="iAs" href="#" target="_blank" itxtdid="3954066">chronic pain</A>, as can result from inflammatory or nerve <A class="iAs" classname="iAs" href="#" target="_blank" itxtdid="3961357">injury</A>, the researchers say, and a potential new target for treating pain</blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://physorg.com/news99758315.html">The finding is a milestone in an investigation the team began several years ago</blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://physorg.com/news99758315.html">It's been known for years that menthol and related cooling agents evoke the psychophysical sensation of cold </blockquote></div><div style="margin: 0px 6px 6px 4px;"><table style="font-size: 11px;border-spacing: 0px;padding: 0px;" cellpadding="0" cellspacing="0" width="100%"><tr><td style="background:transparent;border-width:0px;padding:0px;">&nbsp;</td><td align="right" style="background:transparent;border-width:0px;padding:0px;width:107px" width="107"><a href="http://clipmarks.com/share/1AFCBB65-03F1-4E9A-A7F5-19EA644D4DC0/blog/" title="blog or email this clip"><img src="http://content9.clipmarks.com/images/c2b-foot.png" border="0" alt="blog it" width="107" height="17" style="border-width:0px;padding:0px;margin:0px;" /></a></td></tr></table></div></div>