Gene therapy helps blind see the light


	Gene therapy helps blind see the light

pokkets

4-28-2008 4:59 AM

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4-28-2008 8:19 AM

alanocu

there's an article in the Daily Mail today about a teenager who had this treatment - and it was successful: http://www.dailymail.co.uk/pages/live/articles/news/news.html?in_article_id=562481&in_page_id=1766&ito=1490

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<div style="margin: 12px 0px; font-family: arial; color: #333333; background: #ffffff; border: solid 4px #e5e5e5; width: 100%; clear: left;"><div class="CM_CTB_Content_Wrap" style="margin: 0px; padding: 0px;background-color: #ffffff;"><div style="border-bottom: solid 1px #dcdcdc; white-space: nowrap; margin-bottom: 8px; background-color: #eeeeee ;background-image: url(http://www.clipmarks.com/images/source-bg.gif); background-repeat: repeat-x; height: 24px; line-height: 24px; vertical-align: middle; padding-bottom: 4px; color: #666666; font-size: 10px;" ><a href="http://clipmarks.com/clip-to-blog/" title="see clips that are hot right now"><img src="http://content.clipmarks.com/blog_embed/1ae94cff-c5e5-45f9-86a8-e89ee4c0085d/2BA6D692-F034-4869-8D7F-1B9B787C547C/" alt="" width="19" height="19" border="0" style="vertical-align: middle; margin: 0px 4px; display: inline; border: none; float:none;" /></a>clipped from <a title="http://www.abc.net.au/science/articles/2008/04/28/2228962.htm?site=science&topic=latest" href="http://www.abc.net.au/science/articles/2008/04/28/2228962.htm?site=science&topic=latest" style="font-size: 11px;">www.abc.net.au</a></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.abc.net.au/science/articles/2008/04/28/2228962.htm?site=science&topic=latest"> Deena Beasley and Ben Hirschler</blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.abc.net.au/science/articles/2008/04/28/2228962.htm?site=science&topic=latest"><P class="first">Gene therapy for a rare type of inherited blindness has improved the vision of four patients, boosting hopes for the troubled field of gene repair technology, scientists say.</P></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.abc.net.au/science/articles/2008/04/28/2228962.htm?site=science&topic=latest"><div align="center"><img src="http://content8.clipmarks.com/blog_cache/www.abc.net.au/img/B017EE15-B38A-4C7A-B9F2-1B2721BCCADD" alt="eye" /></div></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.abc.net.au/science/articles/2008/04/28/2228962.htm?site=science&topic=latest">Gene therapy in preliminary, short-term trials has improved the vision of a handful of people with a rare but serious form of blindness. But much work is needed before this approach becomes routine</blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.abc.net.au/science/articles/2008/04/28/2228962.htm?site=science&topic=latest"><P>Two separate teams of doctors report successes in using gene therapy to treat Leber's congenital amaurosis, or LCA.</P></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.abc.net.au/science/articles/2008/04/28/2228962.htm?site=science&topic=latest"><P>LCA damages light receptors in the retina. It usually begins affecting sight in early childhood and causes total blindness by the age of 30. There is no treatment.</P></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.abc.net.au/science/articles/2008/04/28/2228962.htm?site=science&topic=latest"><P>Both teams used a common cold virus to deliver a normal version of one damaged gene that causes the disease, called RPE65, directly into patients' eyes.</P></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.abc.net.au/science/articles/2008/04/28/2228962.htm?site=science&topic=latest"><P>"This result is important for the entire field of gene therapy," says High, a former president of the <A target="_blank" href="http://www.asgt.org/">American Society of Gene Therapy</A>.</P></blockquote></div><div style="margin: 0px 6px 6px 4px;"><table style="font-size: 11px;border-spacing: 0px;padding: 0px;" cellpadding="0" cellspacing="0" width="100%"><tr><td style="background:transparent;border-width:0px;padding:0px;">&nbsp;</td><td align="right" style="background:transparent;border-width:0px;padding:0px;width:107px" width="107"><a href="http://clipmarks.com/share/2BA6D692-F034-4869-8D7F-1B9B787C547C/blog/" title="blog or email this clip"><img src="http://content9.clipmarks.com/images/c2b-foot.png" border="0" alt="blog it" width="107" height="17" style="border-width:0px;padding:0px;margin:0px;" /></a></td></tr></table></div></div>

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