Effects of social isolation traced to brain hormone


	Effects of social isolation traced to brain hormone

wildcat

11-15-2007 4:35 AM

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tags:

social isolation, hormones, psychology, stress, anxiety, aggression

wildcat says:

Humans respond to similar stress in very similar ways

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11-16-2007 2:54 PM

tidbit2

the need to be connected

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<div style="margin: 12px 0px; font-family: arial; color: #333333; background: #ffffff; border: solid 4px #e5e5e5; width: 100%; clear: left;"><div class="CM_CTB_Content_Wrap" style="margin: 0px; padding: 0px;background-color: #ffffff;"><div style="border-bottom: solid 1px #dcdcdc; white-space: nowrap; margin-bottom: 8px; background-color: #eeeeee ;background-image: url(http://www.clipmarks.com/images/source-bg.gif); background-repeat: repeat-x; height: 24px; line-height: 24px; vertical-align: middle; padding-bottom: 4px; color: #666666; font-size: 10px;" ><a href="http://clipmarks.com/clip-to-blog/" title="see clips that are hot right now"><img src="http://content.clipmarks.com/blog_embed/f502c5bb-040e-462a-a9b8-08cda71cf817/31EC173E-318C-480F-B2C9-81C1004B6B0B/" alt="" width="19" height="19" border="0" style="vertical-align: middle; margin: 0px 4px; display: inline; border: none; float:none;" /></a>clipped from <a title="http://physorg.com/news114266243.html" href="http://physorg.com/news114266243.html" style="font-size: 11px;">physorg.com</a></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://physorg.com/news114266243.html"><DIV id="Preview"> 
The anxiety and aggression that result from social isolation have been traced to altered levels of an enzyme that controls production of a brain hormone.
</DIV></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://physorg.com/news114266243.html"><DIV>"We use this animal model for human stress because social isolation in both animals and humans can be responsible for a range of psychological effects, including anxiety, aggression and memory impairment," said Dr. Erminio Costa, director of the UIC Psychiatric Institute, professor of biochemistry and one of the authors of the study.
</DIV></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://physorg.com/news114266243.html"><DIV>Previous studies had suggested that the neural pathways that underlie aggression, anxiety and fear include activation of specific types of neural circuitry that leads into the amygdala, the region of the brain responsible for emotion.
</DIV></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://physorg.com/news114266243.html"><DIV>The researchers suggest that the decrease of 5-alpha-reductase type I and the consequent reduction in the hormone may impair the function of circuits leading to the amygdala and explain the aggressive behavior, perhaps related to anxiety, in socially isolated mice.
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