Skeletal Discovery: Bone cells affect metabolism


	Skeletal Discovery: Bone cells affect metabolism

dorine

8-13-2007 11:43 AM

332 views

tags:

bones, health, metabolism, diabetes, research, biology, science

dorine says:

Interesting.

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<div style="margin: 12px 0px; font-family: arial; color: #333333; background: #ffffff; border: solid 4px #e5e5e5; width: 100%; clear: left;"><div class="CM_CTB_Content_Wrap" style="margin: 0px; padding: 0px;background-color:#cccc99;"><div style="border-bottom: solid 1px #dcdcdc; white-space: nowrap; margin-bottom: 8px; background-color: #eeeeee ;background-image: url(http://www.clipmarks.com/images/source-bg.gif); background-repeat: repeat-x; height: 24px; line-height: 24px; vertical-align: middle; padding-bottom: 4px; color: #666666; font-size: 10px;" ><a href="http://clipmarks.com/clip-to-blog/" title="see clips that are hot right now"><img src="http://content.clipmarks.com/blog_embed/d0baa591-fd29-48ca-abf6-5599e31dcae6/4563AAA7-D115-4B4F-877E-2EAA94D759B9/" alt="" width="19" height="19" border="0" style="vertical-align: middle; margin: 0px 4px; display: inline; border: none; float:none;" /></a>clipped from <a title="http://www.sciencenews.org/articles/20070811/fob1.asp" href="http://www.sciencenews.org/articles/20070811/fob1.asp" style="font-size: 11px;">www.sciencenews.org</a></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.sciencenews.org/articles/20070811/fob1.asp"><div align="center"><img src="http://content6.clipmarks.com/blog_cache/www.sciencenews.org/img/50510678-2CAF-4AE0-9952-2E713E8ADCE4" alt="a8732_1705.jpg" /></div></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.sciencenews.org/articles/20070811/fob1.asp"><P class="caption">THE ARM BONE'S CONNECTED. A bone-cell protein called osteocalcin influences energy metabolism through its effects on pancreatic and fat cells.<BR /><SPAN>N. Heim/Columbia Univ. Med. Center</SPAN></P></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.sciencenews.org/articles/20070811/fob1.asp"><STRONG>Patrick Barry</STRONG></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.sciencenews.org/articles/20070811/fob1.asp"><P>If your blood glucose is out of whack, the problem may be in your bones. New research in mice shows that bone cells exert a surprising influence on how the body regulates sugar, energy, and fat.
</P></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.sciencenews.org/articles/20070811/fob1.asp"><P>
The discovery could lead to new ways to treat type 2 diabetes, a disease involving poor regulation of blood glucose. It also means that skeletons act as endocrine organs, which affect other body tissues by releasing hormones into the bloodstream.
</P></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.sciencenews.org/articles/20070811/fob1.asp">It's certainly an exciting breakthrough."</blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.sciencenews.org/articles/20070811/fob1.asp"><P>Osteocalcin, a somewhat enigmatic protein produced only by osteoblasts, seemed like a good hormone candidate, Karsenty says. "[It] has been the flagship molecule of the [bone-research] field for 30 years, but nobody knew what it was doing."
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