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Prions of fungi
shankargallery
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8-19-2007 11:55 AM
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prion
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<div style="margin: 12px 0px; font-family: arial; color: #333333; background: #ffffff; border: solid 4px #e5e5e5; width: 100%; clear: left;"><div class="CM_CTB_Content_Wrap" style="margin: 0px; padding: 0px;background-color: #ffffff;"><div style="border-bottom: solid 1px #dcdcdc; white-space: nowrap; margin-bottom: 8px; background-color: #eeeeee ;background-image: url(http://www.clipmarks.com/images/source-bg.gif); background-repeat: repeat-x; height: 24px; line-height: 24px; vertical-align: middle; padding-bottom: 4px; color: #666666; font-size: 10px;" ><a href="http://clipmarks.com/clip-to-blog/" title="see clips that are hot right now"><img src="http://content.clipmarks.com/blog_embed/5e44b01f-a384-4b18-895b-9c3d11e49fa1/53F2916E-4FEF-4CF8-9C6F-DD45293E91BF/" alt="" width="19" height="19" border="0" style="vertical-align: middle; margin: 0px 4px; display: inline; border: none; float:none;" /></a>clipped from <a title="http://microbiologybytes.wordpress.com/2007/08/17/prions-of-fungi/" href="http://microbiologybytes.wordpress.com/2007/08/17/prions-of-fungi/" style="font-size: 11px;">microbiologybytes.wordpress.com</a></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://microbiologybytes.wordpress.com/2007/08/17/prions-of-fungi/"><H2><A title="Permanent Link to Prions of fungi" rel="bookmark" href="http://microbiologybytes.wordpress.com/2007/08/17/prions-of-fungi/">Prions of fungi</A></H2></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://microbiologybytes.wordpress.com/2007/08/17/prions-of-fungi/"><P class="date">Posted by <A href="http://microbiologybytes.wordpress.com/">ajcann</A> on August 17th, 2007</P></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://microbiologybytes.wordpress.com/2007/08/17/prions-of-fungi/"><div align="center"><img src="http://content9.clipmarks.com/blog_cache/microbiologybytes.wordpress.com/img/69B5B17D-CAFB-43BC-ACA9-C71ACBF3CD27" alt="Prion protein" /></div></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://microbiologybytes.wordpress.com/2007/08/17/prions-of-fungi/"><li style="margin-left:16px;padding-left: 0px;">[URE3] is a prion of the nitrogen catabolism regulator Ure2p</LI> <li style="margin-left:16px;padding-left: 0px;">[<SPAN>PSI+</SPAN>] is a prion of the translation-termination factor Sup35p, which has a parallel beta-sheet structure.</LI> <li style="margin-left:16px;padding-left: 0px;">[<SPAN>PIN+</SPAN>] is a prion of Rnq1p (function unknown)</LI> <li style="margin-left:16px;padding-left: 0px;">[Het-s] is a prion of the heterokaryon incompatibility protein HETs; this prion of apparently benefits its host (<SPAN>Podospora anserina</SPAN>), whereas the [URE3] and [PSI+] prions of <SPAN>Saccharomyces cerevisiae</SPAN> are detrimental.</LI> <li style="margin-left:16px;padding-left: 0px;">[β] is a prion of vacuolar protease B</LI> <li style="margin-left:16px;padding-left: 0px;">[C] is a prion of a mitogen-activated protein kinase kinase kinase</LI></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://microbiologybytes.wordpress.com/2007/08/17/prions-of-fungi/">There are six known prions of fungi, including four self-propagating amyloids and two enzymes that are necessary to activate their inactive precursors:</blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://microbiologybytes.wordpress.com/2007/08/17/prions-of-fungi/"><P><STRONG>elated:</STRONG></p> <UL> <li style="margin-left:16px;padding-left: 0px;"><A href="http://microbiologybytes.wordpress.com/2007/07/23/prions-and-alzheimers-disease/"> Prions and Alzheimers disease</A></LI> <li style="margin-left:16px;padding-left: 0px;"><A href="http://microbiologybytes.wordpress.com/2007/05/04/candidate-prion-disease-vaccine/">Candidate prion disease vaccine</A></LI> <li style="margin-left:16px;padding-left: 0px;"><A href="http://microbiologybytes.wordpress.com/2007/04/02/the-origin-of-bse/">The Origin of BSE</A></LI></UL></blockquote></div><div style="margin: 0px 6px 6px 4px;"><table style="font-size: 11px;border-spacing: 0px;padding: 0px;" cellpadding="0" cellspacing="0" width="100%"><tr><td style="background:transparent;border-width:0px;padding:0px;"> </td><td align="right" style="background:transparent;border-width:0px;padding:0px;width:107px" width="107"><a href="http://clipmarks.com/share/53F2916E-4FEF-4CF8-9C6F-DD45293E91BF/blog/" title="blog or email this clip"><img src="http://content6.clipmarks.com/images/c2b-foot.png" border="0" alt="blog it" width="107" height="17" style="border-width:0px;padding:0px;margin:0px;" /></a></td></tr></table></div></div>
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