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T-cells keep healthy immunce system from detecting tumors
n2teaching
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11-20-2007 10:21 AM
252 views
tags:
tumors
,
immune system
,
healthy people
,
t-cells
,
cancer
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<div style="margin: 12px 0px; font-family: arial; color: #333333; background: #ffffff; border: solid 4px #e5e5e5; width: 100%; clear: left;"><div class="CM_CTB_Content_Wrap" style="margin: 0px; padding: 0px;background-color: #ffffff;"><div style="border-bottom: solid 1px #dcdcdc; white-space: nowrap; margin-bottom: 8px; background-color: #eeeeee ;background-image: url(http://www.clipmarks.com/images/source-bg.gif); background-repeat: repeat-x; height: 24px; line-height: 24px; vertical-align: middle; padding-bottom: 4px; color: #666666; font-size: 10px;" ><a href="http://clipmarks.com/clip-to-blog/" title="see clips that are hot right now"><img src="http://content.clipmarks.com/blog_embed/873acb3c-bd3e-4fb0-b586-8507aea19579/54C40F1A-BFE3-4045-BFFA-8532ACB87590/" alt="" width="19" height="19" border="0" style="vertical-align: middle; margin: 0px 4px; display: inline; border: none; float:none;" /></a>clipped from <a title="http://news.yahoo.com/s/nm/20071120/hl_nm/cancer_tumours_dc" href="http://news.yahoo.com/s/nm/20071120/hl_nm/cancer_tumours_dc" style="font-size: 11px;">news.yahoo.com</a></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://news.yahoo.com/s/nm/20071120/hl_nm/cancer_tumours_dc"><P> LONDON (Reuters) - Researchers looking at immune systems in healthy people have discovered an interaction between two types of cells that may help explain why the body's natural defenses fail to detect and fight tumors. </P></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://news.yahoo.com/s/nm/20071120/hl_nm/cancer_tumours_dc"><SPAN> By Michael Kahn </SPAN></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://news.yahoo.com/s/nm/20071120/hl_nm/cancer_tumours_dc">Mon Nov 19, 7:26 PM ET</blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://news.yahoo.com/s/nm/20071120/hl_nm/cancer_tumours_dc">The findings could lead to better cancer treatments and new targets for drugs, said Leonie Taams, an immunologist at King's College London, who led the study published on Tuesday.</blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://news.yahoo.com/s/nm/20071120/hl_nm/cancer_tumours_dc"><P>The study looked at <SPAN id="lw_1195518557_0" class="yshortcuts">regulatory T-cells</SPAN>, which keep the immune system stable and are key in controlling immune cells called macrophages that cause inflammation. Inflammation is one of the body's first responses when fighting infection.</p> <P>Taams sa</P></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://news.yahoo.com/s/nm/20071120/hl_nm/cancer_tumours_dc"><P>Taams said the study showed that just as regulatory "police officer" T-cells can stop <SPAN id="lw_1195518557_1" class="yshortcuts">killer T-cells</SPAN> from attacking a tumor, they can also shut off macrophages, suppressing inflammation and keeping the body from detecting tumors.</P></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://news.yahoo.com/s/nm/20071120/hl_nm/cancer_tumours_dc"><P>"The regulatory T-cells trick the immune system into thinking there is no problem."</P></blockquote></div><div style="margin: 0px 6px 6px 4px;"><table style="font-size: 11px;border-spacing: 0px;padding: 0px;" cellpadding="0" cellspacing="0" width="100%"><tr><td style="background:transparent;border-width:0px;padding:0px;"> </td><td align="right" style="background:transparent;border-width:0px;padding:0px;width:107px" width="107"><a href="http://clipmarks.com/share/54C40F1A-BFE3-4045-BFFA-8532ACB87590/blog/" title="blog or email this clip"><img src="http://content6.clipmarks.com/images/c2b-foot.png" border="0" alt="blog it" width="107" height="17" style="border-width:0px;padding:0px;margin:0px;" /></a></td></tr></table></div></div>
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