<div style="margin: 12px 0px; font-family: arial; color: #333333; background: #ffffff; border: solid 4px #e5e5e5; width: 100%; clear: left;"><div class="CM_CTB_Content_Wrap" style="margin: 0px; padding: 0px;background-color: #ffffff;"><div style="border-bottom: solid 1px #dcdcdc; white-space: nowrap; margin-bottom: 8px; background-color: #eeeeee ;background-image: url(http://www.clipmarks.com/images/source-bg.gif); background-repeat: repeat-x; height: 24px; line-height: 24px; vertical-align: middle; padding-bottom: 4px; color: #666666; font-size: 10px;" ><a href="http://clipmarks.com/clip-to-blog/" title="see clips that are hot right now"><img src="http://content.clipmarks.com/blog_embed/3a16dcd3-53fc-4dc0-b47d-29bbafa31bff/8D6AD107-C13B-4F69-8873-FD32D944C2B7/" alt="" width="19" height="19" border="0" style="vertical-align: middle; margin: 0px 4px; display: inline; border: none; float:none;" /></a>clipped from <a title="http://www.newscientist.com/article/dn17745-fat-reprograms-genes-linked-to-diabetes.html?DCMP=NLC-nletter&nsref=dn17745" href="http://www.newscientist.com/article/dn17745-fat-reprograms-genes-linked-to-diabetes.html?DCMP=NLC-nletter&nsref=dn17745" style="font-size: 11px;">www.newscientist.com</a></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.newscientist.com/article/dn17745-fat-reprograms-genes-linked-to-diabetes.html?DCMP=NLC-nletter&nsref=dn17745"><H1> Fat reprograms genes linked to diabetes </H1></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.newscientist.com/article/dn17745-fat-reprograms-genes-linked-to-diabetes.html?DCMP=NLC-nletter&nsref=dn17745"><P class="infuse">A <A href="http://www.newscientist.com/topic/genetics" alt="gene" omd="zodJump('http://widgets.zibb.com/images/_jump.gif?tag=InfusionJS&url=http:%2F%2Fwww.newscientist.com%2Ftopic%2Fgenetics&gsid=gene&entitytypeid=kw&lid=http://www.newscientist.com/topic/genetics&title=gene&intref=infusion&variantName=gene&zodid=96')" class="infusionLink">gene</A> that helps muscle cells burn fat can be radically altered and switched off if the cells carrying it are exposed to fat. The finding suggests that the same process may occur when people eat too much fat-rich junk <A href="http://www.newscientist.com/topic/food-drink" alt="food" omd="zodJump('http://widgets.zibb.com/images/_jump.gif?tag=InfusionJS&url=http:%2F%2Fwww.newscientist.com%2Ftopic%2Ffood-drink&gsid=food&entitytypeid=kw&lid=http://www.newscientist.com/topic/food-drink&title=food&intref=infusion&variantName=food&zodid=96')" class="infusionLink">food</A>, resulting in drastic changes to this "fat burning" gene.</P></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.newscientist.com/article/dn17745-fat-reprograms-genes-linked-to-diabetes.html?DCMP=NLC-nletter&nsref=dn17745"><P class="infuse">But proof that components in the diet can permanently alter genes is itself a breakthrough, providing the first evidence that the food we eat may change the function of our DNA. This is a process known as "<A href="http://www.newscientist.com/article/mg19926641.500-rewriting-darwin-the-new-nongenetic-inheritance.html">epigenetics</A>".</P></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.newscientist.com/article/dn17745-fat-reprograms-genes-linked-to-diabetes.html?DCMP=NLC-nletter&nsref=dn17745"><P class="infuse">In this study the <A href="http://www.newscientist.com/topic/genetics" alt="DNA" omd="zodJump('http://widgets.zibb.com/images/_jump.gif?tag=InfusionJS&url=http:%2F%2Fwww.newscientist.com%2Ftopic%2Fgenetics&gsid=DNA&entitytypeid=kw&lid=http://www.newscientist.com/topic/genetics&title=DNA&intref=infusion&variantName=DNA&zodid=96')" class="infusionLink">DNA</A> itself remained unchanged, except for a masking process called methylation which can permanently mothball a gene by capping individual chemical units, or bases.</P></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.newscientist.com/article/dn17745-fat-reprograms-genes-linked-to-diabetes.html?DCMP=NLC-nletter&nsref=dn17745"><P class="infuse">"The palmitic acid essentially switches off the gene," says Zierath. The same thing happened on exposure to tumour necrosis factor-alpha, a substance produced by white blood cells to help fight infection.</P></blockquote></div><div style="margin: 0px 6px 6px 4px;"><table style="font-size: 11px;border-spacing: 0px;padding: 0px;" cellpadding="0" cellspacing="0" width="100%"><tr><td style="background:transparent;border-width:0px;padding:0px;">&nbsp;</td><td align="right" style="background:transparent;border-width:0px;padding:0px;width:107px" width="107"><a href="http://clipmarks.com/share/8D6AD107-C13B-4F69-8873-FD32D944C2B7/blog/" title="blog or email this clip"><img src="http://content8.clipmarks.com/images/c2b-foot.png" border="0" alt="blog it" width="107" height="17" style="border-width:0px;padding:0px;margin:0px;" /></a></td></tr></table></div></div>

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