'Protein-friendly' chip offers rapid disease testing


	'Protein-friendly' chip offers rapid disease testing

tabsey

2-29-2008 7:33 AM

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science, medical

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<div style="margin: 12px 0px; font-family: arial; color: #333333; background: #ffffff; border: solid 4px #e5e5e5; width: 100%; clear: left;"><div class="CM_CTB_Content_Wrap" style="margin: 0px; padding: 0px;background-color: #ffffff;"><div style="border-bottom: solid 1px #dcdcdc; white-space: nowrap; margin-bottom: 8px; background-color: #eeeeee ;background-image: url(http://www.clipmarks.com/images/source-bg.gif); background-repeat: repeat-x; height: 24px; line-height: 24px; vertical-align: middle; padding-bottom: 4px; color: #666666; font-size: 10px;" ><a href="http://clipmarks.com/clip-to-blog/" title="see clips that are hot right now"><img src="http://content.clipmarks.com/blog_embed/b0e2d4e0-24d7-4c21-a6ed-2c503598c477/9230133F-96D0-4EE4-B980-387A8AD1B70B/" alt="" width="19" height="19" border="0" style="vertical-align: middle; margin: 0px 4px; display: inline; border: none; float:none;" /></a>clipped from <a title="http://technology.newscientist.com/channel/tech/dn13391-proteinfriendly-chip-offers-rapid-disease-testing.html?feedId=online-news_rss20" href="http://technology.newscientist.com/channel/tech/dn13391-proteinfriendly-chip-offers-rapid-disease-testing.html?feedId=online-news_rss20" style="font-size: 11px;">technology.newscientist.com</a></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://technology.newscientist.com/channel/tech/dn13391-proteinfriendly-chip-offers-rapid-disease-testing.html?feedId=online-news_rss20"><P>A device capable of spotting diseases in the tiniest drop of blood or urine has been developed by UK scientists. It is 10 times smaller than existing sensors and can detect a range of protein molecules associated with different diseases.</P></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://technology.newscientist.com/channel/tech/dn13391-proteinfriendly-chip-offers-rapid-disease-testing.html?feedId=online-news_rss20"><P><A target="ns" href="http://www.eenweb.leeds.ac.uk/profile.php?id=1026">Christoph Wälti</A> and <A target="ns" href="http://www.personal.leeds.ac.uk/~eenagd/AGD.html">Giles Davies</A> and colleagues at the University of Leeds used electrodes instead of conventional glass slides to make their device.</P></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://technology.newscientist.com/channel/tech/dn13391-proteinfriendly-chip-offers-rapid-disease-testing.html?feedId=online-news_rss20"><P>The electrodes are only about 10 micrometers apart and could ultimately be made even smaller, they say.</P></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://technology.newscientist.com/channel/tech/dn13391-proteinfriendly-chip-offers-rapid-disease-testing.html?feedId=online-news_rss20"><P>Existing sensors use antibodies that bind to target proteins. But antibodies are unstable and become poorer at identifying disease proteins when attached to components within a sensor.</P></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://technology.newscientist.com/channel/tech/dn13391-proteinfriendly-chip-offers-rapid-disease-testing.html?feedId=online-news_rss20"><P>At present, scientists must also label proteins with fluorescent tags and then use optical techniques to detect them – a process that looks at just one protein at a time and is both complex and imprecise.</P></blockquote></div><div style="margin: 0px 6px 6px 4px;"><table style="font-size: 11px;border-spacing: 0px;padding: 0px;" cellpadding="0" cellspacing="0" width="100%"><tr><td style="background:transparent;border-width:0px;padding:0px;">&nbsp;</td><td align="right" style="background:transparent;border-width:0px;padding:0px;width:107px" width="107"><a href="http://clipmarks.com/share/9230133F-96D0-4EE4-B980-387A8AD1B70B/blog/" title="blog or email this clip"><img src="http://content8.clipmarks.com/images/c2b-foot.png" border="0" alt="blog it" width="107" height="17" style="border-width:0px;padding:0px;margin:0px;" /></a></td></tr></table></div></div>

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