Gene Editing Could Make Anyone Immune to AIDS


	Gene Editing Could Make Anyone Immune to AIDS

wildcat

7-1-2008 11:31 AM

918 views

tags:

dna, hiv, immunity, viruses

2 Comments |

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7-1-2008 10:10 PM

pokkets

So getting a 'Nip and a Tuck', will take on a whole new meaning.

7-5-2008 12:48 AM

meancookie89

and somehow the public is blind to this as wealthy drug peddlers and the FDA chuckle at our sheer apathy!

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<div style="margin: 12px 0px; font-family: arial; color: #333333; background: #ffffff; border: solid 4px #e5e5e5; width: 100%; clear: left;"><div class="CM_CTB_Content_Wrap" style="margin: 0px; padding: 0px;background-color: #ffffff;"><div style="border-bottom: solid 1px #dcdcdc; white-space: nowrap; margin-bottom: 8px; background-color: #eeeeee ;background-image: url(http://www.clipmarks.com/images/source-bg.gif); background-repeat: repeat-x; height: 24px; line-height: 24px; vertical-align: middle; padding-bottom: 4px; color: #666666; font-size: 10px;" ><a href="http://clipmarks.com/clip-to-blog/" title="see clips that are hot right now"><img src="http://content.clipmarks.com/blog_embed/a8eb9d40-4e50-4bf5-b5ac-6a23722101e2/96690D2B-E606-4B86-B504-6ACDBCD14CEC/" alt="" width="19" height="19" border="0" style="vertical-align: middle; margin: 0px 4px; display: inline; border: none; float:none;" /></a>clipped from <a title="http://blog.wired.com/wiredscience/2008/06/gene-editing-co.html" href="http://blog.wired.com/wiredscience/2008/06/gene-editing-co.html" style="font-size: 11px;">blog.wired.com</a></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://blog.wired.com/wiredscience/2008/06/gene-editing-co.html"><div align="center"><img src="http://content9.clipmarks.com/blog_cache/blog.wired.com/img/1D295323-5B57-4946-8A98-C70F73A3DC6E" alt="Zfn" /></div></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://blog.wired.com/wiredscience/2008/06/gene-editing-co.html"><P>Some people have a mutation that makes them amazingly resistant to HIV -- and now, scientists may have found a way to give that immunity to anyone. </P></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://blog.wired.com/wiredscience/2008/06/gene-editing-co.html"><P>Viruses enter cells and take them over, but to get inside, they need a handhold. HIV pulls itself in by grabbing onto a protein called CCR5, which decorates the surface of T-cells, which are one of the two major types of white blood cells and play an important role in helping the body fight infections. Back in the 1990's, researchers took interest in a handful of promiscuous gay men who were able to engage in sexual relations with their HIV-positive partners with impunity. Most of them <A href="http://www.ncbi.nlm.nih.gov/pubmed/8756719" linkindex="45">had a mutation</A> that kept their cells from producing normal CCR5 protein. </P></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://blog.wired.com/wiredscience/2008/06/gene-editing-co.html">Armed with that knowledge, scientists have developed several tactics to block the production of CCR5 or perturb its shape so that the HIV virus can't grab onto it during the first step of its hijacking attempt</blockquote></div><div style="margin: 0px 6px 6px 4px;"><table style="font-size: 11px;border-spacing: 0px;padding: 0px;" cellpadding="0" cellspacing="0" width="100%"><tr><td style="background:transparent;border-width:0px;padding:0px;">&nbsp;</td><td align="right" style="background:transparent;border-width:0px;padding:0px;width:107px" width="107"><a href="http://clipmarks.com/share/96690D2B-E606-4B86-B504-6ACDBCD14CEC/blog/" title="blog or email this clip"><img src="http://content6.clipmarks.com/images/c2b-foot.png" border="0" alt="blog it" width="107" height="17" style="border-width:0px;padding:0px;margin:0px;" /></a></td></tr></table></div></div>

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