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Scientists Uncover Deadly Ebola Virus's "Achilles' Heel"
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7-11-2008 8:09 AM
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<div style="margin: 12px 0px; font-family: arial; color: #333333; background: #ffffff; border: solid 4px #e5e5e5; width: 100%; clear: left;"><div class="CM_CTB_Content_Wrap" style="margin: 0px; padding: 0px;background-color: #ffffff;"><div style="border-bottom: solid 1px #dcdcdc; white-space: nowrap; margin-bottom: 8px; background-color: #eeeeee ;background-image: url(http://www.clipmarks.com/images/source-bg.gif); background-repeat: repeat-x; height: 24px; line-height: 24px; vertical-align: middle; padding-bottom: 4px; color: #666666; font-size: 10px;" ><a href="http://clipmarks.com/clip-to-blog/" title="see clips that are hot right now"><img src="http://content.clipmarks.com/blog_embed/48242e24-df5f-4d7d-976e-405c0cf265df/9CBF7CDF-D42C-490D-9926-0CEE64BBF737/" alt="" width="19" height="19" border="0" style="vertical-align: middle; margin: 0px 4px; display: inline; border: none; float:none;" /></a>clipped from <a title="http://www.sciam.com/article.cfm?id=scientists-uncover-deadly&sc=rss" href="http://www.sciam.com/article.cfm?id=scientists-uncover-deadly&sc=rss" style="font-size: 11px;">www.sciam.com</a></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.sciam.com/article.cfm?id=scientists-uncover-deadly&sc=rss"><div align="center"><img src="http://content8.clipmarks.com/blog_cache/www.sciam.com/img/270F19FF-B4DF-483D-8BAA-0CD68629E2DB" alt="ebola protein" /></div></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.sciam.com/article.cfm?id=scientists-uncover-deadly&sc=rss"><P class="caption" id="articleImgCap"><STRONG>EBOLA'S WEAPON:</STRONG> Researchers have determined the structure of the protein that kicks-off the process by which Ebola infects cells.<BR /><SPAN>C. Corbaci and E. Ollmann Saphire</SPAN></P></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.sciam.com/article.cfm?id=scientists-uncover-deadly&sc=rss"><DIV>In a breakthrough that could eventually help tame one of the deadliest virsuses known to man, researchers have laid bare the key to <A href="http://www.sciam.com/article.cfm?id=new-clues-to-ebolas-feroc">Ebola's power</A>: a lone protein that resides on its surface. The discovery paves the way for new treatments that target and destroy the designated culprit, rendering impotent a virus that, though rare, can kill up to 90 percent of the people it infects.</DIV></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.sciam.com/article.cfm?id=scientists-uncover-deadly&sc=rss"><DIV> The so-called Ebola virus glycoprotein, or "spike protein," was first discovered a decade ago and has been a target for scientists attempting to <A href="http://www.sciam.com/article.cfm?id=an-uncertain-defense">design </A><A href="http://www.sciam.com/topic.cfm?id=vaccines">vaccines</A> and therapies to prevent it from infecting cells. But, until now, researchers did not understand the protein's structure—and thus, the best way to attack it.</DIV></blockquote></div><div style="margin: 0px 6px 6px 4px;"><table style="font-size: 11px;border-spacing: 0px;padding: 0px;" cellpadding="0" cellspacing="0" width="100%"><tr><td style="background:transparent;border-width:0px;padding:0px;"> </td><td align="right" style="background:transparent;border-width:0px;padding:0px;width:107px" width="107"><a href="http://clipmarks.com/share/9CBF7CDF-D42C-490D-9926-0CEE64BBF737/blog/" title="blog or email this clip"><img src="http://content6.clipmarks.com/images/c2b-foot.png" border="0" alt="blog it" width="107" height="17" style="border-width:0px;padding:0px;margin:0px;" /></a></td></tr></table></div></div>
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