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'Designer mice' work wins Nobel prize
pokkets
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2
10-8-2007 10:34 PM
206 views
tags:
nobel prize
,
medicine
,
physiology
,
mice
,
genestem cell
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<div style="margin: 12px 0px; font-family: arial; color: #333333; background: #ffffff; border: solid 4px #e5e5e5; width: 100%; clear: left;"><div class="CM_CTB_Content_Wrap" style="margin: 0px; padding: 0px;background-color: #ffffff;"><div style="border-bottom: solid 1px #dcdcdc; white-space: nowrap; margin-bottom: 8px; background-color: #eeeeee ;background-image: url(http://www.clipmarks.com/images/source-bg.gif); background-repeat: repeat-x; height: 24px; line-height: 24px; vertical-align: middle; padding-bottom: 4px; color: #666666; font-size: 10px;" ><a href="http://clipmarks.com/clip-to-blog/" title="see clips that are hot right now"><img src="http://content.clipmarks.com/blog_embed/3b7da66d-3107-4a5b-a77e-f0b048b17f0a/A5C99EA9-CF52-487F-AD0D-DBD486D266B3/" alt="" width="19" height="19" border="0" style="vertical-align: middle; margin: 0px 4px; display: inline; border: none; float:none;" /></a>clipped from <a title="http://www.abc.net.au/science/news/stories/2007/2054445.htm" href="http://www.abc.net.au/science/news/stories/2007/2054445.htm" style="font-size: 11px;">www.abc.net.au</a></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.abc.net.au/science/news/stories/2007/2054445.htm"><DIV align="left" class="byline">Maggie Fox</DIV></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.abc.net.au/science/news/stories/2007/2054445.htm"><DIV>The gene-targeting technique that helped scientists create 'designer mice' has won its developers this year's Nobel Prize in Medicine or Physiology.</DIV></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.abc.net.au/science/news/stories/2007/2054445.htm"><div align="center"><img src="http://content7.clipmarks.com/blog_cache/www.abc.net.au/img/D63A1155-4261-4342-91BE-DCCF866DAD3D" alt="mouse" /></div></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.abc.net.au/science/news/stories/2007/2054445.htm"><DIV>The technique is used by scores of labs across the world and has helped pin down the function of 10,000 different genes.</DIV></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.abc.net.au/science/news/stories/2007/2054445.htm">Three researchers were awarded the prize for their work, which was done separately but when taken together made possible the 'knock-out' mice that are now key to basic medical research</blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.abc.net.au/science/news/stories/2007/2054445.htm">Professor Martin Evans of the UK's <A target="_blank" href="http://www.cf.ac.uk/">Cardiff University</A> laid the groundwork by discovering and isolating embryonic stem cells in mice,</blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.abc.net.au/science/news/stories/2007/2054445.htm"><DIV>Evans figured out how to genetically tinker with the cells and implant these altered embryos into foster mothers, which gave birth to mice with the desired genetic changes.</DIV></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.abc.net.au/science/news/stories/2007/2054445.htm">Professor Mario Capecchi of the US <A target="_blank" href="http://www.hhmi.org/">Howard Hughes Medical Institute</A> and the <A target="_blank" href="http://www.utah.edu">University of Utah</A> and Professor Oliver Smithies of the <A target="_blank" href="http://www.unc.edu/">University of North Carolina</A> independently developed precise ways to disable</blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.abc.net.au/science/news/stories/2007/2054445.htm">a single chosen gene.</blockquote></div><div style="margin: 0px 6px 6px 4px;"><table style="font-size: 11px;border-spacing: 0px;padding: 0px;" cellpadding="0" cellspacing="0" width="100%"><tr><td style="background:transparent;border-width:0px;padding:0px;"> </td><td align="right" style="background:transparent;border-width:0px;padding:0px;width:107px" width="107"><a href="http://clipmarks.com/share/A5C99EA9-CF52-487F-AD0D-DBD486D266B3/blog/" title="blog or email this clip"><img src="http://content8.clipmarks.com/images/c2b-foot.png" border="0" alt="blog it" width="107" height="17" style="border-width:0px;padding:0px;margin:0px;" /></a></td></tr></table></div></div>
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