Scientists Make Headway in Understanding Alzheimer's


	Scientists Make Headway in Understanding Alzheimer's

SenorCoconut

2-6-2009 9:57 AM

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tags:

bag2, alzheimer's

SenorCoconut says:

Scientists have discovered that a protein called BAG2 is important for understanding Alzheimer's and may open up new targets for treatment.

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2-6-2009 5:51 PM

masbury

Clever "head"line!

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<div style="margin: 12px 0px; font-family: arial; color: #333333; background: #ffffff; border: solid 4px #e5e5e5; width: 100%; clear: left;"><div class="CM_CTB_Content_Wrap" style="margin: 0px; padding: 0px;background-color: #ffffff;"><div style="border-bottom: solid 1px #dcdcdc; white-space: nowrap; margin-bottom: 8px; background-color: #eeeeee ;background-image: url(http://www.clipmarks.com/images/source-bg.gif); background-repeat: repeat-x; height: 24px; line-height: 24px; vertical-align: middle; padding-bottom: 4px; color: #666666; font-size: 10px;" ><a href="http://clipmarks.com/clip-to-blog/" title="see clips that are hot right now"><img src="http://content.clipmarks.com/blog_embed/c01c1ab7-0c50-4474-982c-d0c65283c570/C96924B9-169E-4D95-9444-2EC01CA05C06/" alt="" width="19" height="19" border="0" style="vertical-align: middle; margin: 0px 4px; display: inline; border: none; float:none;" /></a>clipped from <a title="http://www.elements4health.com/scientists-make-headway-in-understanding-alzheimers-.html" href="http://www.elements4health.com/scientists-make-headway-in-understanding-alzheimers-.html" style="font-size: 11px;">www.elements4health.com</a></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.elements4health.com/scientists-make-headway-in-understanding-alzheimers-.html"><div align="center"><img src="http://content6.clipmarks.com/blog_cache/www.elements4health.com/img/D7B5806F-4F57-458A-A1A2-5477EBCCF1D6" alt="brain cranial nerves" /></div></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.elements4health.com/scientists-make-headway-in-understanding-alzheimers-.html">Scientists have discovered that a protein called BAG2 is important for understanding Alzheimer's and may open up new targets for treatment. They are ready to move from studying these proteins in culture to finding out how they work with mice.</blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.elements4health.com/scientists-make-headway-in-understanding-alzheimers-.html"><DIV>
The image depicts the cranial nerves of a normal human brain.</DIV></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.elements4health.com/scientists-make-headway-in-understanding-alzheimers-.html">The protein tau is normally found in brain cells, but scientists don't know why it clumps into tangles in people with Alzheimer's.</blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.elements4health.com/scientists-make-headway-in-understanding-alzheimers-.html"><DIV>
The research team recently started to work on BAG2 to find out how it may be involved in the removal of tangled tau. "It turns out that when you put this protein into the cell, it clears away the damaged tau very nicely.  It doesn't clear away all the tau; it goes for the damaged tau protein and removes it.” </DIV></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.elements4health.com/scientists-make-headway-in-understanding-alzheimers-.html">This is a protein that is involved in neurofibrillary tangles, so now we have a new target for treatment discovery. This is not a treatment, just a new target. The new target is BAG2</blockquote></div><div style="margin: 0px 6px 6px 4px;"><table style="font-size: 11px;border-spacing: 0px;padding: 0px;" cellpadding="0" cellspacing="0" width="100%"><tr><td style="background:transparent;border-width:0px;padding:0px;">&nbsp;</td><td align="right" style="background:transparent;border-width:0px;padding:0px;width:107px" width="107"><a href="http://clipmarks.com/share/C96924B9-169E-4D95-9444-2EC01CA05C06/blog/" title="blog or email this clip"><img src="http://content7.clipmarks.com/images/c2b-foot.png" border="0" alt="blog it" width="107" height="17" style="border-width:0px;padding:0px;margin:0px;" /></a></td></tr></table></div></div>

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