An Alzheimer's Conflict Of Interest


	An Alzheimer's Conflict Of Interest

Matthew Herper

4-8-2008 10:25 AM

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Matthew Herper says:

Adam Feuerstein discovers that a key researcher's status as a consultant to Elan and Wyeth was not properly disclosed in a medical journal article.

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<div style="margin: 12px 0px; font-family: arial; color: #333333; background: #ffffff; border: solid 4px #e5e5e5; width: 100%; clear: left;"><div class="CM_CTB_Content_Wrap" style="margin: 0px; padding: 0px;background-color: #ffffff;"><div style="border-bottom: solid 1px #dcdcdc; white-space: nowrap; margin-bottom: 8px; background-color: #eeeeee ;background-image: url(http://www.clipmarks.com/images/source-bg.gif); background-repeat: repeat-x; height: 24px; line-height: 24px; vertical-align: middle; padding-bottom: 4px; color: #666666; font-size: 10px;" ><a href="http://clipmarks.com/clip-to-blog/" title="see clips that are hot right now"><img src="http://content.clipmarks.com/blog_embed/8ff78ddc-66ad-453d-9916-cc32f35b3b98/D170AA9B-A917-4CA3-8363-0D79E398CA8D/" alt="" width="19" height="19" border="0" style="vertical-align: middle; margin: 0px 4px; display: inline; border: none; float:none;" /></a>clipped from <a title="http://www.thestreet.com/story/10410647/1/elan-and-wyeth-had-ties-to-studys-authors.html?puc=lhhome" href="http://www.thestreet.com/story/10410647/1/elan-and-wyeth-had-ties-to-studys-authors.html?puc=lhhome" style="font-size: 11px;">www.thestreet.com</a></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.thestreet.com/story/10410647/1/elan-and-wyeth-had-ties-to-studys-authors.html?puc=lhhome"><P>An Alzheimer's disease research paper published last year in a prestigious medical journal failed to disclose the financial ties one of the co-authors had to <B>Elan</B> <SPAN class="TICKERFLAT" id="ELN">(<A href="http://www.thestreet.com/quote/ELN.html?omorig=story">ELN</A> - <A href="http://www.thestreet.com/cramerstake/ELN.html">Cramer's Take</A> - <A href="http://www.stockpickr.com/thestreet-symbol/ELN/">Stockpickr</A>)</SPAN> and <B>Wyeth</B> <SPAN class="TICKERFLAT" id="WYE">(<A href="http://www.thestreet.com/quote/WYE.html?omorig=story">WYE</A> - <A href="http://www.thestreet.com/cramerstake/WYE.html">Cramer's Take</A> - <A href="http://www.stockpickr.com/thestreet-symbol/WYE/">Stockpickr</A>)</SPAN> as a paid consultant to the drugmakers.
</P></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.thestreet.com/story/10410647/1/elan-and-wyeth-had-ties-to-studys-authors.html?puc=lhhome"><P>The paper in the September 2007 <I>Archives of Neurology</I>, a journal published by the American Medical Association, describes the use of a new test -- the neuropsychological test battery (NTB) -- to measure the memory and mental status of patients with Alzheimer's disease. 
</P></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.thestreet.com/story/10410647/1/elan-and-wyeth-had-ties-to-studys-authors.html?puc=lhhome">John Harrison, the consultant, was paid by Elan and Wyeth to create the NTB as a new cognitive test for the company's experimental Alzheimer's drug, bapineuzumab. </blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.thestreet.com/story/10410647/1/elan-and-wyeth-had-ties-to-studys-authors.html?puc=lhhome"><P>"The drafts of our manuscript specifically included reference to the fact that I had received payment from both Elan and Wyeth, though for some reason this disclosure does not appear in the published manuscript," said Harrison in an email response to questions. 
</P></blockquote></div><div style="margin: 0px 6px 6px 4px;"><table style="font-size: 11px;border-spacing: 0px;padding: 0px;" cellpadding="0" cellspacing="0" width="100%"><tr><td style="background:transparent;border-width:0px;padding:0px;">&nbsp;</td><td align="right" style="background:transparent;border-width:0px;padding:0px;width:107px" width="107"><a href="http://clipmarks.com/share/D170AA9B-A917-4CA3-8363-0D79E398CA8D/blog/" title="blog or email this clip"><img src="http://content7.clipmarks.com/images/c2b-foot.png" border="0" alt="blog it" width="107" height="17" style="border-width:0px;padding:0px;margin:0px;" /></a></td></tr></table></div></div>

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