sublingual administration


	sublingual administration

patrizia777

6-19-2008 8:49 AM

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patrizia777 says:

definition+efficacy

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<div style="margin: 12px 0px; font-family: arial; color: #333333; background: #ffffff; border: solid 4px #e5e5e5; width: 100%; clear: left;"><div class="CM_CTB_Content_Wrap" style="margin: 0px; padding: 0px;background-color: #ffffff;"><div style="border-bottom: solid 1px #dcdcdc; white-space: nowrap; margin-bottom: 8px; background-color: #eeeeee ;background-image: url(http://www.clipmarks.com/images/source-bg.gif); background-repeat: repeat-x; height: 24px; line-height: 24px; vertical-align: middle; padding-bottom: 4px; color: #666666; font-size: 10px;" ><a href="http://clipmarks.com/clip-to-blog/" title="see clips that are hot right now"><img src="http://content.clipmarks.com/blog_embed/9078a2ff-243a-431e-8e6d-9661922f524a/E6144D05-9B49-46EA-97E2-0102EE78FA75/" alt="" width="19" height="19" border="0" style="vertical-align: middle; margin: 0px 4px; display: inline; border: none; float:none;" /></a>clipped from <a title="http://abdellab.sunderland.ac.uk/lectures/Parmacology/Introdoc/sublingual.html" href="http://abdellab.sunderland.ac.uk/lectures/Parmacology/Introdoc/sublingual.html" style="font-size: 11px;">abdellab.sunderland.ac.uk</a></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://abdellab.sunderland.ac.uk/lectures/Parmacology/Introdoc/sublingual.html"><table background="undefined" bgcolor=""><tr><TD><P><FONT size="2" face="Verdana, Arial, Helvetica, sans-serif" color="#ff9900"><STRONG>Sublingual 
        administration </STRONG></FONT></p> <P><FONT size="2" face="Verdana, Arial, Helvetica, sans-serif" color="#ffffff">This 
        form of administration avoids the mixing of drug with food and/or gastric 
        juices which may impede absorption.</FONT></p> <P><FONT size="2" face="Verdana, Arial, Helvetica, sans-serif" color="#ffffff">The 
        surfaces of the mouth or buccal area that can absorb chemicals include 
        the tongue (especially under the tongue) and gums. The terms used for 
        top and bottom of the tongue administration are <FONT color="#ff0000">superlingual</FONT> 
        and <FONT color="#ff0000">sublingual</FONT>, respectively.</FONT></p> <P><FONT size="2" face="Verdana, Arial, Helvetica, sans-serif" color="#ffffff"> 
        <FONT color="#99ccff"><STRONG>Nitroglycerin</STRONG></FONT>, a potent 
        <FONT color="#ff0000">vasodilator</FONT>, used to be given for <A href="#">angina</A> 
        (heart pain) exclusively by <FONT color="#ff0000">sublingual</FONT> tablets. 
        The large advantage to sublingual administration is a <FONT color="#ff0000">faster 
        route</FONT> to the heart itself via the blood circulation.</FONT></p> <P><FONT size="2" face="Verdana, Arial, Helvetica, sans-serif" color="#ffffff">Sublingual 
        administration has a special significance since venous drainage from the 
        mouth is to the superior <A href="#">vena 
        cava</A>, the drug is protected from first-pass metabolism of the liver.</FONT></P></TD></tr></table></blockquote></div><div style="margin: 0px 6px 6px 4px;"><table style="font-size: 11px;border-spacing: 0px;padding: 0px;" cellpadding="0" cellspacing="0" width="100%"><tr><td style="background:transparent;border-width:0px;padding:0px;">&nbsp;</td><td align="right" style="background:transparent;border-width:0px;padding:0px;width:107px" width="107"><a href="http://clipmarks.com/share/E6144D05-9B49-46EA-97E2-0102EE78FA75/blog/" title="blog or email this clip"><img src="http://content6.clipmarks.com/images/c2b-foot.png" border="0" alt="blog it" width="107" height="17" style="border-width:0px;padding:0px;margin:0px;" /></a></td></tr></table></div></div>

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