"Speaking at the O'Reilly Emerging Technology Conference this past March, Peter Norvig, Google's research director, offered an update to George Box's maxim: "All models are wrong, and increasingly you can succeed without them."

Very interesting approach. It seems we have reached a state of knowledge where mathematical modeling greatly departs from our ability to form causative explanations. This is a deep conceptual departure, where the very meaning of the word 'understanding' should be revised. However it might well be that this is just a symptom of an intelligence gap. We simply need to be more intelligent in order to understand the world at the level of complexity accessible to us now. Perhaps it is a really good reason why we need an AGI (Artificial General Intelligence).