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POPSThe World's First Flying Saucer: Made Right Here on Earth Using an onboard source of energy (such as a battery, ultracapacitor, solar panel or any combination thereof), the electrodes will send an electrical current into the plasma, causing the plasma to push against the neutral (noncharged) air surrounding the craft, theoretically generating enough force for liftoff and movement in different directions (depending on where on the craft's surface you direct the electrical current). The concept sounds far-fetched, but U.F. mechanical and aerospace engineering associate professor Subrata Roy plans to have a mini model ready to demonstrate his theory within the next year.
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POPSCan Recycling Be Used To Treat Cancer? The researchers discovered a compound, STF-62247, that was selectively toxic to RCCs deficient in VHL whereas cells with normal VHL were not affected. Treatment of RCC cells lacking functional VHL induced autophagy, a cellular recycling process that cells normally use to conserve resources during times of stress. "Increasing evidence implicates a role for autophagy in cancer, but it is not well understood how cellular and environmental cues drive autophagic cells down survival or death pathways," explains Dr. Giaccia. The researchers demonstrated that STF-62247 enhanced autophagy in VHL-deficient cells while inhibition of the autophagy pathway significantly increased the survival of VHL-deficient cells treated with STF-62247. "We have found a small molecule that selectively induces cell death in VHL-deficient cells, such as those that are found in kidney cancer. This represents a paradigm shift for targeted therapy," concludes Dr. Giaccia.
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