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POPSAcadia Schizophrenia Drug Fails Acadia does a nice job not spinning the results. (See the press release below.) The company has another drug, pimavanserin, in trials for psychosis related to Parkinson's. That drug is also being tested for schizophrenia as an add-on to other therapies. What's interesting is that the failed drug, ACP-104, was a metabolite of Clozapine, a very effective antipsychotic with harsh side effects. In theory, using the metabolite should result in a better drug, but it doesn't always work out this way. Sometimes, as in this case, you get something that's not effective at all. That's a painful reminder of how little we know about biology and chemistry and how much sheer luck is still involved in inventing new medicines.
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POPSA Writer's Damaged Sword Arm in New Orleans
An excellent story by an excellent writer--she goes on (but read all): Every other house is either empty or boarded up, and ongoing reconstruction seems either non-existent or delayed. Potholes and uneven surfaces threaten to peel off her car’s exhaust system. A few residents are valiantly planting spring flowers in muddy yards, and the riot of color draws the eyes away from the wrecked buildings. Every block or so, there are one or two homes that are miraculously restored, or appear to have escaped the wrath of Poseidon. This street is one of those that had boats going door to door in the aftermath of Katrina’s flood, and the flat the writer is renting has no furniture because the owner lost almost everything to the filthy water. The furniture that is left has been destroyed by a contractor who neglected to cover it while he was working. The writer feels narcissistic, wanting to complain about having nothing except a musty mattress on the floor. There are tens of thousands here
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POPSODE PAGE Great Outdoors Group on Yahoo! You should check it out! http://groups.yahoo.com/group/Outdoorsencounters/
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