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POPS22 Foods With Trans Fat Trans fat can make food taste good, last longer on grocery-store shelves, and more hazardous for your heart. "Trans fats raise your bad cholesterol just like saturated fats, but they also increase inflammation and lower the good cholesterol that protects us against heart disease," says Andrea Giancoli, R.D., M.P.H., a spokesperson for the American Dietetic Association, in Hermosa Beach, Calif.